Chromatography Gels - Irregular Shape

Manufactured for over 40 years and offered under the brand name ZEOprep, Zeochem’s irregular shape silica gel is one of the most widely used chromatography sorbents in the world. It is available as unbonded and bonded chromatography gel.

Custom Solutions

Your one-stop shop for your process-scale chromatography needs.

ZEOprep, ZEObeads and ZEOsphere excel in their efficiency to create the best filtration, separation and purification solutions for a large variety of compounds and/or industries.

  • ZEOprep Unbonded Silica
  • ZEOprep Bonded Silica
  • ZEOprep 60 C18 / 40-63um
  • ZEOprep 60 C8 / 40–63µm
  • ZEOprep 60 NH2 / 40-63um
  • ZEOprep 60 NH2P / 40–63µm
  • ZEOprep 60 Diol / 40-63um
  • ZEOprep 60 SH / 40-63um
  • ZEOprep 60 CN / 40-63um
  • ZEOprep 60 SAX / 40-63um
  • ZEOprep 90 C18 / 40-63um
  • ZEOprep 90 C8 / 40-63um
  • ZEOprep 90 C18 / 60-200um
  • ZEOprep 90 NH2 / 40-63um
  • ZEOprep 90 CN / 40–63µm

ZEOprep Unbonded Silica

Unbonded ZEOprep silica is mostly used as column packing material for preparative chromatography and the purification of natural products, food and cosmetic ingredients, as well as in the purification of active pharmaceutical and nutraceutical ingredients.

The unbonded silica is produced in a broad spectrum of various pore sizes, particle size distributions and residual water contents. These modifications make ZEOprep the preferred choice for a wide array of applications. ZEOprep materials work efficiently under various separation conditions; diverse types of solvents, columns and pressure designs; and different types of crude or target compounds.

Our standard product portfolio can provide an appropriate phase when it comes to preparative column chromatography, flash cartridge packing and lab kit packing or batch-type scavenging steps, adding highest reproducibility of separation, efficient purification and reliable analytical results. We also offer large batch sizes to facilitate the bulk use of silica gel in industrial applications. In addition to our standard products, we offer customized silicas.

Our standard range of ZEOprep silica gel includes 60 angstrom and 90 angstrom pore sizes at various particle size distributions.

ZEOprep Bonded Silica

Bonded ZEOprep silica is used in liquid chromatography, flash chromatography and solid phase extraction. It can be used as scavengers and in chromatographic purifications steps when manufacturing active pharmaceutical ingredients (APIs).

The vast ZEOprep product range provides outstanding lot-to-lot homogeneity based on defined quality parameters that ensure reproducibility in large-scale industrial applications. Our products also provide the most reliable separation power in commonly used techniques such as flash chromatography as well as in analytical applications.

The bonded silica features chemically modified silica gels which can be used in reversed-phase or normal-phase chromatography. Our expertise in bonding silica gels is based on decades of experience. We guarantee a high and efficient bonding ratio, chemical and mechanical stability, and excellent loadability. We can provide bulk quantities with large single-batch sizes, ensuring material uniformity and highly reproducible results.

Besides the standard 60 angstrom or 90 angstrom modifications of 40–63µm and 60–200µm particle size distributions, we also offer customized modifications. Additionally, our bonded silica is available with or without end capping.

ZEOprep 60 C18 / 40-63um

Alkyl-bonded silica for reversed-phase chromatography is a robust and reliable packing material, widely used in industrial separations as well as in flash chromatography.

ZEOprep 60 C8 / 40–63µm

Alkyl-bonded silica with shorter chain length and slightly reduced hydrophobicity which is used in reversed-phase chromatography. The shorter alkyl length allows for better interaction between stationary phase and the target compound.

ZEOprep 60 NH2 / 40-63um

Amine-bonded silica is mostly used in normal-phase chromatography and serves as an efficient metal scavenger in batch applications, best for removing metals such as nickel.

ZEOprep 60 NH2P / 40–63µm

Primary, secondary amine-bonded silica and is more polar than C18/C8 phases. It is used in reversed-phase as well in normal-phase chromatography.

ZEOprep 60 Diol / 40-63um

Diol-bonded silica, more polar than C18/C8 types. Used in reversed- as well as in normal-phase chromatography, it is the product of choice for acid-sensitive compounds.

ZEOprep 60 SH / 40-63um

Thiol-bonded silica most efficiently serves as a metal scavenger, but it is also used as a means to remove palladium in batch applications.

ZEOprep 60 CN / 40-63um

Cyan-bonded silica is more polar than C18/8 bonding but is mostly used in reversed-phase chromatography for polar compounds and for a broader range of pH environment.

ZEOprep 60 SAX / 40-63um

Silica-bonded for anion exchange chromatography.

ZEOprep 90 C18 / 40-63um

Alkyl-bonded silica with 90 angstrom pore size that has proved to be a robust packing material in particular for flash cartridges.

ZEOprep 90 C8 / 40-63um

Alkyl-bonded silica with 90 angstrom pore size with shorter alkyl chain length and slightly reduced hydrophobicity. It is used in reversed-phase chromatography. The shorter alkyl length allows for better interaction between stationary phase and the target compound.

ZEOprep 90 C18 / 60-200um

Alkyl-bonded silica with 90 angstrom pore size and a larger particle size distribution which provides a higher flow rate under low-pressure applications.

ZEOprep 90 NH2 / 40-63um

Amine-bonded silica with 90 angstrom pore size, mostly used in normal phase chromatography. It serves as an efficient metal scavenger in batch applications and is best for removing nickel.

ZEOprep 90 CN / 40–63µm

Cyan-bonded silica with 90 angstrom pore size, more polar than C18/8 bonding but mostly used in reversed-phase chromatography for polar compounds and in a broader range of pH environment.

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